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American Society of Microbiology ABMM Sample Questions (Q134-Q139):
NEW QUESTION # 134
A clinical microbiology laboratory is performing antimicrobial susceptibility testing on a Streptococcus pneumoniae isolate using broth microdilution. The lowest concentration of antibiotic that inhibits visible growth of the organism is reported as the:
- A. Minimum bactericidal concentration (MBC)
- B. Breakpoint
- C. Minimum inhibitory concentration (MIC)
- D. Zone diameter
Answer: C
NEW QUESTION # 135
A research team is investigating the mechanisms of antifungal resistance in Candida albicans. They identify a strain that exhibits resistance to azole antifungal agents. Further analysis reveals overexpression of a specific ATP-binding cassette (ABC) transporter protein in the resistant strain. This mechanism of resistance involves:
- A. Modification of the fungal cell wall, preventing azole penetration.
- B. Increased degradation of the azole antifungal agent within the fungal cell.
- C. Alteration of the fungal ergosterol biosynthesis pathway, the target of azoles.
- D. Active efflux of the azole antifungal agent out of the fungal cell.
Answer: D
NEW QUESTION # 136
Lyme disease, characterized initially by erythema migrans, is caused by Borrelia burgdorferi. What is the primary arthropod vector responsible for transmitting this spirochete to humans in the Northeastern United States?
- A. Pulex irritans (Human flea)
- B. Amblyomma americanum (Lone Star tick)
- C. Dermacentor variabilis (American dog tick)
- D. Ixodes scapularis (Blacklegged tick)
Answer: D
NEW QUESTION # 137
A clinical microbiology laboratory is implementing whole-genome sequencing (WGS) for enhanced surveillance of Listeria monocytogenes isolates associated with foodborne outbreaks. WGS provides several advantages over traditional subtyping methods like pulsed-field gel electrophoresis (PFGE). Which of the following is the MOST significant advantage of WGS in this context?
- A. Faster turnaround time for obtaining results.
- B. Easier standardization and inter-laboratory comparison of data.
- C. Higher discriminatory power for resolving phylogenetic relationships and identifying outbreakclusters.
- D. Lower cost per isolate compared to PFGE.
Answer: C
NEW QUESTION # 138
A patient develops a severe skin and soft tissue infection following a boating accident in the Gulf Coast.
Wound cultures grow a Gram-negative, halophilic bacterium that is oxidase-positive. The MOST likely organism is:
- A. Vibrio vulnificus
- B. Aeromonas hydrophila
- C. Pseudomonas aeruginosa
- D. Shewanella putrefaciens
Answer: A
NEW QUESTION # 139
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